Behaviorists believe that much of car sickness in dogs is caused by fear, so to overcome this problem, you will need to slowly teach your dog not to be afraid of the car.
Here's how to teach him the car is a great place:
Begin by just rewarding your dog for being near the car, then for voluntarily getting in, then reward him when you turn on the engine, and continue, like so, in baby steps. Feed him his meals in the car - but not right before a trip, of course!. In fact, avoid feeding your dog less than one hour before car rides to lessen the effects of any nausea.
Avoid taking your dog for trips that you think will result in him becoming sick while you are teaching him not to be afraid. Each time he gets carsick will set back your progress in teaching him that the car is a safe place.
Some other things that may be helpful:
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